Baroreflex Activation Therapy in Patients With Heart Failure With Reduced Ejection Fraction
نویسندگان
چکیده
منابع مشابه
Baroreflex Activation Therapy for the Treatment of Heart Failure With a Reduced Ejection Fraction.
OBJECTIVES The objective of this clinical trial was to assess the safety and efficacy of carotid BAT in advanced HF. BACKGROUND Increased sympathetic and decreased parasympathetic activity contribute to heart failure (HF) symptoms and disease progression. Baroreflex activation therapy (BAT) results in centrally mediated reduction of sympathetic outflow and increased parasympathetic activity. ...
متن کاملChronic heart failure with reduced ejection fraction.
Heart failure with reduced ejection fraction is a clinical syndrome of dysp nea, exercise intolerance and/or edema resulting from an impairment of ejec tion of blood, usually documented by a left ventricular ejection fraction of 40% or less on echocardiography.1,2 Cor on ary artery disease is a major cause; therefore, stress testing or, in the pres ence of angina, coronary angiography shoul...
متن کاملOral Iron Therapy for Heart Failure With Reduced Ejection Fraction
Impaired exercise capacity is a cardinal manifestation of heart failure (HF) that is closely related to reduced quality of life and poor outcomes. Therapeutic options beyond neurohormonal blockade to improve functional capacity and symptoms in HF are currently limited and must be pursued. Iron deficiency is associated with reduced functional capacity and poorer quality of life in HF. Here, a ra...
متن کاملBaroreflex activation therapy: a new approach to the management of advanced heart failure with reduced ejection fraction
: Chronic heart failure is a common clinical condition characterized by persistent excessive sympathetic nervous system activation. The derangement of the sympathetic activity has relevant implications for disease progression and patient survival. Aiming to positively impact patient outcome, autonomic nervous system modulatory therapies have been developed and tested in animal and clinical stud...
متن کاملBaroreflex activation therapy for the treatment of heart failure with a reduced ejection fraction: safety and efficacy in patients with and without cardiac resynchronization therapy.
AIMS Increased sympathetic and decreased parasympathetic activity contribute to heart failure (HF) symptoms and disease progression. Carotid baroreceptor stimulation (baroreflex activation therapy, BAT) results in centrally mediated reduction of sympathetic and increase in parasympathetic activity. Because patients treated with cardiac resynchronization therapy (CRT) may have less sympathetic/p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2020
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2020.05.015